Cardioprotective Effects of Melatonin in Reperfusion Injury
نویسندگان
چکیده
منابع مشابه
Cardioprotective Effects of Melatonin in Reperfusion Injury
DOI: 10.5935/abc.20180011 The possibility of limiting ischemic myocardial injury has been a major focus of cardiovascular research over 4 decades and literally thousands of interventions have been tested in this direction.1 Unfortunately, this has been a long, unsolved saga, and, apart from reperfusion, most interventions have been largely unsuccessful at the clinical arena.1 With the advent of...
متن کاملMelatonin Protective Effects against Liver Ischemia/Reperfusion Injury
Hepatic ischemia-reperfusion (I/R) is a common phenomenon during liver surgery, transplantation, infection and trauma which results in damage and necrosis of the hepatic tissue through different pathways. Mechanisms involved in I/R damage are very intricate and cover several aspects. Several factors are involved in I/R-induced damages; briefly, decrease in sinusoidal perfusion and ATP generatio...
متن کاملCardioprotective Effects of Quercetin in Cardiomyocyte under Ischemia/Reperfusion Injury
Quercetin, a polyphenolic compound existing in many vegetables, fruits, has antiinflammatory, antiproliferation, and antioxidant effect on mammalian cells. Quercetin was evaluated for protecting cardiomyocytes from ischemia/reperfusion injury, but its protective mechanism remains unclear in the current study. The cardioprotective effects of quercetin are achieved by reducing the activity of Src...
متن کاملCardioprotective effects of tilianin in rat myocardial ischemia-reperfusion injury.
Tilianin, the main effective flavonoid monomer enriched from Dracocephalum moldavuca L., has been shown to have cardioprotective effects. However, the mechanism of tilianin cardioprotection remains largely unknown. The present study aimed to investigate the effects of tilianin preconditioning on myocardial ischemia/reperfusion injury and to analyze the possible mechanism of action. A total of 4...
متن کاملCardioprotective effects of luteolin during ischemia-reperfusion injury in rats.
BACKGROUND Antioxidants effectively reduce ischemia-reperfusion (IR) injury. The cardioprotective effects of luteolin, a flavonoid that exhibits antioxidant properties and is widely available in many fruits and vegetables, were examined in rats subjected to myocardial IR injury. METHODS AND RESULTS Rats were subjected to myocardial ischemia or reperfusion injury to evaluate the antiarrhythmic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arquivos Brasileiros de Cardiologia
سال: 2017
ISSN: 0066-782X
DOI: 10.5935/abc.20180011